Home-Based Training With Feedback to Improve Outcomes in Adolescents and Young Adults With Cerebral Palsy.. (THRIVE-CP)

University of Copenhagen

Status: Begins enrollment in 6 months

Conditions: Cerebral Palsy

Treatments: Behavioral: Music Motion Group; Behavioral: Control

Study type: Interventional

Funder types: Other

Identifiers

NCT06962618

THRIVE-CP

Details and patient eligibility

About

This clinical trial aims to determine whether extrinsic feedback through music enhances the effects of home-based motor training for adolescents and young adults with cerebral palsy (CP) and whether feedback improves adherence to the training program.

The main questions it aims to answer are:

• Does extrinsic feedback improve real-world movement more than home training alone?
• Do participants receiving extrinsic feedback adhere more closely to their training program?

To determine its effectiveness, the investigators will compare home-based training with and without real-time music feedback.

Participants will:

• Engage in a home-based motor training program for 12 weeks, tailored to their individual needs and goals.
• Receive real-time music feedback during training or no feedback (control group).
• Attend weekly virtual coaching sessions to discuss short-term goals and training progress.
• Undergo movement assessments before training, at 12 weeks (T2) and 24 weeks (T3).
• Wear movement sensors for 72 hours at T2 and T3 to track real-world movement behavior.

Enrollment: 70 estimated patients

Sex: All

Ages: 15 to 25 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of cerebral palsy
• Sensorimotor deficits in at least one limb
• Demonstrated motivation to develop or regain motor skills, indicated by the expression of specific goals
• Ability to follow instructions independently or with caregiver support
• Ability to provide informed consent

Exclusion criteria

• Diagnosis of dyskinetic cerebral palsy
• Presence of significant health risks that could interfere with participation
• Surgery or first Botox injection within one month before the trial or during the trial period

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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70 participants in 2 patient groups

Music Motion Group

Experimental group

Treatment:

Behavioral: Music Motion Group

Control

Active Comparator group

Treatment:

Behavioral: Control