Home-based Transcranial Static Magnetic Field Stimulation (tSMS) of the Supplementary Motor Area in Parkinson's Disease

Fundación de investigación HM

Status and phase: Enrolling; Phase 1

Conditions: Parkinson's Disease

Treatments: Device: Transcranial static magnetic field stimulation (tSMS) of the supplementary motor area

Study type: Interventional

Funder types: Other

Identifiers

NCT06840678

1715-GHM

Details and patient eligibility

About

This is a pilot open study to test the hypothesis that home-based transcranial static magnetic field stimulation (tSMS) of the supplementary motor area is safe and feasible to modulate corticostriatal activity in patients with Parkinson's disease.

Enrollment: 20 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• idiopathic Parkinson's disease (Brain Bank criteria)
• optimal clinical response to dopaminergic medication (>30% MDS-UPDRS-III improvement)

Exclusion criteria

• MRI-incompatible metal objects in the body (e.g. cardiac pacemakers)
• presence of levodopa-induced dyskinesias
• other main neuropsychiatric co-morbidity

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

tSMS

Experimental group

Description:

30 min of tSMS, 5 daily sessions per week (monday to friday), for 8 weeks, at home

Treatment:

Device: Transcranial static magnetic field stimulation (tSMS) of the supplementary motor area