Home Sleep and Metabolism

The University of Chicago

Status

Completed

Conditions

Overweight

Sleep

Treatments

Other: sleep

Study type

Interventional

Funder types

Other

Identifiers

NCT02253368

IRB14-0528

Details and patient eligibility

About

Bedtimes and wake-up times vary from person to person. The aim of this research is to examine the associations between sleep habits and metabolism in healthy people. In this study, the investigators will collect information on sleep-wake habits and how the body uses energy.

Enrollment

210 patients

Sex

All

Ages

21 to 40 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Age: 21-40 years
Body mass index: 25.0 to 29.9 kg/m2
Average habitual sleep duration of 6.5 hours or less per night (as confirmed by actigraphy)
stable sleep habits for the past 6 months

Exclusion criteria

obstructive sleep apnea or history of any other sleep disorder
night or rotating shift work (current or in the past 2 years)
habitual daytime naps
recent (< 4 week) travel across time zones
extreme chronotypes
any acute or chronic medical condition
diabetes
prior or current eating or psychiatric disorders
claustrophobia
irregular menstrual periods, menopause, pregnancy,
alcohol abuse, excessive caffeine intake, smoking, illegal drug use
subjects who are currently following a weight loss regimen or any other special diet or exercise programs
subjects who have received iv or oral contrast in the past 2 weeks
use of any prescription medication that can affect sleep or metabolism with the exception of antihypertensive and lipid lowering agents as follows. Subjects who are taking anti-hypertensive medication and/or lipid-lowering agents will be included only if they are well controlled and on a stable regimen (no change in medications in the previous 3 months). However, beta-blockers and thiazide diuretics will not be allowed, as these medications are known to affect insulin sensitivity. Women will be required to not be on hormone replacement therapy.