Homeopathic Treatment of Children Suffering From PFAPA (HOMPFAPA)

Michael Frass

Status: Completed

Conditions: Periodic Fever Syndrome

Treatments: Drug: Homeopathic Globule

Study type: Observational

Funder types: Other

Identifiers

NCT05995288

202308

Details and patient eligibility

About

Periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis (PFAPA) syndrome is frequently diagnosed in young children. Fevers recurring at a nearly predictable rate every three to eight weeks are the signature symptom of PFAPA syndrome. PFAPA is an acquired autoinflammatory disorder, which recurs in association with at least one sign of aphthous stomatitis, pharyngitis, and cervical lymph node enlargement. The aim of this retrospective case report is to gain an impression of the course of disease during individualized homeopathic treatment in children suffering from PFAPA.

Full description

In this retrospective study, the investigators collected the history and symptoms of 13 consecutive PFAPA patients. The investigators also described the individually chosen homeopathic medicinal products (HMPs) used, as well as the course of the disease. Clinical outcome of case reports was assessed using the "Modified Naranjo Criteria for Homeopathy-Causal Attribution Inventory". Eight points are taken as the threshold for the possible correlation between homeopathic therapy and improvement of symptoms or cure in chronic cases

Enrollment: 13 patients

Sex: All

Ages: 1 to 10 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Children suffering from fever with at least one of the symptooms of PFAPA besides fever

Exclusion criteria

Parents not willing to sign informed consent.

Trial design

13 participants in 1 patient group

Children suffering from PFAPA

Description:

Children suffering from periodic fever, with at least one of the following symptoms: aphthous stomatitis, pharyngitis, cervical adenitis

Treatment:

Drug: Homeopathic Globule