Honey Dressing - A Preventive Procedure for Post-Surgical Site Infection.

HITEC-Institute of Medical Sciences

Status and phase: Completed; Phase 3; Phase 2

Conditions: Wound Surgical; Wound Dehiscence; Wound Bleeding; Wound Infection

Treatments: Biological: Honey Dressing; Drug: Iodine Dressing

Study type: Interventional

Funder types: Other

Identifiers

NCT06220344

HITEC-IMS-01-2022

Details and patient eligibility

About

The goal of this clinical trial is to compare the wound healing in the participants who underwent the clean surgical procedure, by applying honey dressing and common Iodine solution dressing, participants will have no other co-morbidities like Diabetes, Anemia, etc. which can make the results biased. The main questions it aims to answer are:

• Do the iodine solutions are enough to counter the infections caused by resistant strains of bacteria?
• What is the efficacy and efficiency of honey dressing in wound care?

Participants will be tasked to

• Ensure strict follow-up in the hospital dressing room
• Half of the participants will apply common iodine solution dressing and the other half will be applied honey dressing.

Researchers will compare Iodine dressing (Control group) with Honey dressing (Experimental group) to see if Honey dressing is better in the prevention of post-surgery wound infection and if it is cost-efficient and its efficacy.

Enrollment: 80 patients

Sex: All

Ages: 12 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Patients with sterile/clean post-surgical wounds are admitted in general surgery, neurosurgery, orthopedic, and gynecology wards and require follow-up dressings.

Exclusion criteria

1. Patients with:

   • Anemia
   • BMI>30
   • Local Infection in wound area.
   • Venous leg ulcers
   • Diabetes
   • Immunocompromised (Oncological patients)

2. Patient under negative pressure therapy

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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80 participants in 2 patient groups

Honey

Experimental group

Description:

Participants will get honey dressings in their follow-up visits to the dressing room.

Treatment:

Biological: Honey Dressing

Aseptic Iodine

Active Comparator group

Description:

Participants will get iodine solution dressings in their follow-up visits to the dressing room.

Treatment:

Drug: Iodine Dressing