Horizontal Mattress vs. Interrupted Suture in Surgical Techniques of Pancreaticojejunostomy

Wakayama Medical University

Status and phase: Unknown; Phase 3

Conditions: Patients Who Undergo Pancreatoduodenectomy

Treatments: Procedure: pancreaticojejunostomy with horizontal mattress suture; Procedure: pancreaticojejunostomy with interrupted suture

Study type: Interventional

Funder types: Other

Identifiers

NCT01898780

HOMING

Details and patient eligibility

About

The aim of this study is to verify that the frequency of pancreatic fistula (ISGPF grade B and C) in horizontal mattress suture are lower than in interrupted suture during pancreaticojejunostomy in pancreatoduodenectomy by randomized clinical trial.

Enrollment: 190 estimated patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Patients from whom we obtained written informed consent of this study

Exclusion criteria

• Patients with severe ischemic cardiac disease
• Patients with severe liver damage
• Patients requiring oxygen administration due to interstitial pneumonia or pulmonary fibrosis
• Patients requiring dialysis treatment due to chronic renal failure
• Patients who are considered as inappropriate by attending physician

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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190 participants in 2 patient groups

horizontal mattress

Experimental group

Description:

pancreaticojejunostomy with horizontal mattress suture

Treatment:

Procedure: pancreaticojejunostomy with horizontal mattress suture

interrupted suture

Experimental group

Description:

pancreaticojejunostomy with interrupted suture

Treatment:

Procedure: pancreaticojejunostomy with interrupted suture