Hormonal and Metabolic Effects of Weight Loss

Charité University Medicine Berlin

Status: Completed

Conditions: Obesity

Treatments: Behavioral: lifestyle

Study type: Interventional

Funder types: Other

Identifiers

NCT00953264

EA4/042/07

Details and patient eligibility

About

The investigators here propose to evaluate the hormonal and metabolic effects of weight loss, including evaluation of changes in several tissues.

Enrollment: 290 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI > 27 kg/m2 (adults)

Exclusion criteria

• pregnancy, breastfeeding

• patients with:

  • heart failure
  • impaired hepatic or renal function
  • anaemia
  • disturbed coagulation
  • infection, malabsorption
  • severe hypertension
  • any other endocrine disorder

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

290 participants in 1 patient group

life style intervention

Experimental group

Treatment:

Behavioral: lifestyle