Hospital- and Home-Based Structured Pulmonary Rehabilitation in Recently Admitted COPD Patients: A Quasi-Experimental Study at Assiut University

Assiut University

Status: Begins enrollment in 2 months

Conditions: COPD

Treatments: Behavioral: Pulmonary Rehabilitation

Study type: Interventional

Funder types: Other

Identifiers

NCT07197229

Combined Pulmonary Rehabilitat

Details and patient eligibility

About

This study evaluates the effect of a structured three-month pulmonary rehabilitation (PR) program, delivered both in-hospital and at home, on exercise capacity, respiratory symptoms, and functional status in stable COPD patients.

Full description

Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of mortality and morbidity worldwide, significantly reducing patients' physical activity and quality of life. This study investigates a tailored pulmonary rehabilitation program combining hospital-based and home-based components over 12 weeks. The hospital component includes patient education, nutritional support, structured exercise training for both upper and lower limbs, and smoking cessation strategies. The home program emphasizes continuity with daily walking, strength exercises, and lifestyle modifications. The program aims to improve exercise capacity, dyspnea scores, and quality of life. Assessments include the six-minute walk test (6MWT), CAT score, mMRC dyspnea scale, spirometry, arterial blood gas analysis, and the St George's Respiratory Questionnaire. Measurements are collected at baseline and after program completion to assess improvements.

Enrollment: 70 estimated patients

Sex: All

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Stable COPD patients diagnosed based on spirometry (post-bronchodilator FEV1/FVC <70%)

Age > 40 years

Moderate to severe COPD stage

Able and willing to participate in rehabilitation program

Exclusion criteria

• Age < 40 years

Current acute COPD exacerbation at enrollment

Significant comorbid conditions limiting participation (e.g., uncontrolled diabetes mellitus, uncontrolled hypertension, left-sided heart failure, renal failure, liver cell failure)

Neuromuscular diseases, severe cognitive impairment, or psychiatric disturbance

Pregnant patients

Unwilling to participate in the rehabilitation program

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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70 participants in 1 patient group

patients diagnosed with moderate-to-severe COPD (confirmed by spirometry) who are clinically stable

Experimental group

Description:

Participants undergo a 12-week structured PR program including both hospital-based sessions (education, structured exercise, nutrition counseling, smoking cessation) and home-based exercises (daily walking, strength training progression).

Treatment:

Behavioral: Pulmonary Rehabilitation