Hospital In-Patient Insulin Study

The Royal Bournemouth Hospital

Status and phase: Terminated; Phase 4

Conditions: Diabetes Mellitus, Type 2

Treatments: Drug: Detemir

Study type: Interventional

Funder types: Other

Identifiers

NCT00135070

H.P.I.1

Details and patient eligibility

About

Hyperglycaemia has been shown to increase morbidity and mortality in patients with critical illness, myocardial infarction and stroke. This study aims to look at patients with hyperglycaemia and reduce their blood sugar levels using differing combinations of subcutaneous and intravenous insulin.

Full description

This is a randomised trial involving patients with type II diabetes who are brought into the hospital with a problem other than a diabetic emergency. Patients will be included, who have a blood sugar > than 17mmols. They will be randomised to one of two groups and either given intravenous or subcutaneous insulin. Outcome measures are length of stay, glucose control and comparison of the two regimens. Cost implications will also be analysed.

Enrollment: 41 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Type II diabetes
• Blood glucose > 17mmols

Exclusion criteria

• Type I diabetes
• Hyperosmolar non-ketotic coma (HONK)
• Diabetic ketoacidosis (DKA)
• Myocardial infarction (MI)
• Vomiting

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)