Hot Water Drinking Therapy in Achalasia (AHW)

Chinese Academy of Medical Sciences & Peking Union Medical College

Status: Unknown

Conditions: Achalasia

Treatments: Procedure: Pneumatic dilation; Other: hot water drinking therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT01863966

PUMCH-AchaWater

Details and patient eligibility

About

From clinical observation that some achalasia patients drink water to help swallow food, the investigators have proposed a systemic hot water drinking therapy. This study is to observe its efficacy on achalasia symptoms and explore its mechanism.

Full description

1. Achalasia patients will participate hot water drinking therapy: to drink 200ml of hot water before and after a meal, as well as 2 hours before sleep and to chew food carefully and swallow with hot soup.
2. Patients are followed by achalasia associated symptom scores, barium esophagram and endoscopy.
3. If patients are unsatisfied with hot water drinking therapy, they receive pneumatic dilation

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• achalasia patients diagnosed by endoscopy, barium esophagram and manometry

Exclusion criteria

• could not drink water
• poor compliance
• severe comorbidities
• esophageal stenosis secondary to erosions and cancer

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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100 participants in 2 patient groups

Hot water drinking therapy

Experimental group

Description:

Hot water drinking before,after meal and before sleep

Treatment:

Other: hot water drinking therapy

Pneumatic dilation

Active Comparator group

Description:

Patients who are unsatisfied with hot water drinking therapy are to receive standard pneumatic dilation

Treatment:

Procedure: Pneumatic dilation