How Common is Hypoglycaemia in Older People With Diabetes Who Fall?

University of East Anglia

Status

Completed

Conditions

Diabetes

Hypoglycaemia

Treatments

Device: Continuous glucose monitoring (Dexcom G6)

Study type

Interventional

Funder types

Other

Identifiers

NCT05470842

Details and patient eligibility

About

The purpose of this study is to use 24 hour continuous glucose monitoring in older patients with diabetes who present with symptoms of falls, or dizziness, or confusion, that may indicate hypoglycaemia.

Full description

Background and study aims Patients with diabetes can be treated with medications (such as insulin or sulfonylureas) that can lower the sugar levels too much (hypos). A hypo means that the brain does not get enough energy. A person can become confused, dizzy, pass out, and/or have a fall.

Older people with diabetes often seek treatment in hospital for symptoms such as falls, dizziness or feeling muddled. Health care professionals will order tests to investigate the possible causes for the fall, being muddled or dizzy, which can include a review of medications, checking blood pressures and the heart.

However, it has previously been difficult to obtain 24-hour blood sugar monitoring in older people with diabetes to check if hypos could be an important contributing factor to their falls and dizzy spells.

Continuous Glucose Monitoring (CGM) allows non-stop monitoring with a sensor that sits just under the skin. This sends sugar readings to a smartphone every few minutes (via Bluetooth) for 10 days. This enables full evaluation of the amount of time a person's sugar is in the target range, and the time in the low/high ranges. Medical research with CGM has revealed that some older people are suffering from substantial periods of hypos that they are not aware of.

During this study, older people with diabetes will be asked to wear a CGM device for 10 days to investigate possibility of hypos.

Enrollment

12 patients

Sex

All

Ages

75+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

75 years and older with diabetes
Treated with glucose-medications which carry a high risk of hypoglycaemia (sulfonylureas and/or insulin)
Presenting to hospital with a fall and/or symptoms suggestive of unrecognised hypoglycaemia (such as dizziness, feeling muddled).

Exclusion criteria

Treatment with metformin alone
Lack of capacity,
Not willing to participate,
Terminal illness (less than one-year life expectancy).
Evidence of bruising, bleeding, cellulitis and/or skin tears on the upper arms or abdomen.