How Important Are Hematological Parameters in the Prognosis of Severe Covid-19 Patients?

Hisar Intercontinental Hospital

Status: Completed

Conditions: COVID-19

Treatments: Diagnostic Test: Hemogram

Study type: Observational

Funder types: Other

Identifiers

NCT05650944

HisarIH-125

Details and patient eligibility

About

It is aimed to reveal the treatment and prognostic values by evaluating the differences in hematological parameters and indices, especially in dead Covid-19 cases.

Material Method: It is planned to retrospectively examine the hemogram parameters of 125 male, 44 female and 169 critical Covid-19 patients hospitalized between 01.03.2020 and 31.12.2021. Subjects were divided into 2 groups as deceased (77) and living (92) patients according to demographic data such as age and gender.

Statistical evaluation: All analyzes were SPSS 25.0, Kolmogorov Smirnov test was used to determine distribution, median and interquartile range (Tukey's Hinges Percentile) were used to summarize variables. The differences between the Independent-Samples Mann Whitney U Test and the data of the patient groups and the optimal cut-off values, sensitivity and specificity values will be determined by ROC analysis. It will be considered statistically significant when the p value is below 0.05 (with the two-tailed test)

Full description

The aim of this study is to examine the effectiveness of routine laboratory complete blood count parameters and rates as diagnostic and prognostic criteria in severe COVID-19.

Enrollment: 125 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients over the age of 18
2. Critical patients taken to intensive care
3. The length of stay in the ICU is more than 24 hours

Exclusion criteria

1. Patients under 18 years of age (2) Patients with hematological malignancies (3) The length of stay in the ICU is less than 24 hours.

Trial design

125 participants in 2 patient groups

Covid-19 Survivor groups

Description:

Covid-19 survivor groups are hematological parameters

Treatment:

Diagnostic Test: Hemogram

Covid-19 Non-survivor groups

Description:

Hematological parameters in patients with severe COVID-19 who have died.

Treatment:

Diagnostic Test: Hemogram