How Improvement in Control of Diabetes Influences the Production of a Hormone Produced in the Gut Which Improves the Release and Action of Insulin. (MSD-GLP1)

The Royal Bournemouth Hospital

Status: Completed

Conditions: Type 2 Diabetes Mellitus

Treatments: Drug: Sitagliptin; Drug: Glimepiride

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT00747383

08/H0201/57

Details and patient eligibility

About

The study is aimed at Type 2 Diabetics who are taking Metformin, but whose Diabetes remains poorly controlled. There are two additional medications already in use, Glimepiride and Sitagliptin will be compared to assess levels of improvement in Diabetes control.

Enrollment: 74 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diabetes Mellitus
• Currently on Metformin but poor glycaemic control,

Exclusion criteria

• Under 18 years of age

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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74 participants in 2 patient groups

1

Active Comparator group

Treatment:

Drug: Glimepiride

2

Active Comparator group

Treatment:

Drug: Sitagliptin