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How Long Must the MRI Follow-up Last to Safely Identify Middle Ear Residual Cholesteatoma

University Hospital Center (CHU) logo

University Hospital Center (CHU)

Status

Completed

Conditions

Middle Ear Cholesteatoma

Study type

Observational

Funder types

Other

Identifiers

NCT04489550
RECHMPL20_0224

Details and patient eligibility

About

Previous studies demonstrated the high diagnostic value of non-echoplanar diffusion weighted magnetic resonance imaging (non-EP DWI) for residual cholesteatoma. However, limited data are available regarding a suitable length of imaging follow-up. The present study aimed to determine the optimal duration of non-EP DWI follow-up for residual cholesteatoma

Full description

A retrospective, monocentric study was performed between 2013 and 2019 and included all patients regularly followed-up after canal wall-up tympanoplasty with at least two non-EP DWI performed on the same 1.5T MRI scanner. MR images were reviewed independently by two radiologists. Sensitivity and specificity values were calculated as a function of time after the surgery. Receiver operating characteristics (ROC) curves were analyzed to determine the optimal follow-up duration.

Enrollment

17 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

  • patients regularly followed-up for middle ear cholesteatoma, who underwent two or more non-EP DWI performed on the same 1.5 Tesla MRI scanner

Exclusion criteria

  • congenital cholesteatomas, tympanoplasty with canal wall-down technique, or suspicion of residual cholesteatoma on the first MRI follow-up

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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