How Microbes and Metabolism May Predict Skin Cancer Immunotherapy Outcomes (MINING)

The Washington University

Status: Terminated

Conditions: Squamous Cell Carcinoma of the Skin; Melanoma; Autoimmunity; Skin Cancer; Basal Cell Carcinoma; Merkel Cell Carcinoma

Treatments: Biological: Immunotherapy

Study type: Observational

Funder types: Other

Identifiers

NCT03370861

MINING

Details and patient eligibility

About

The purpose of this research study is to examine the relationship between the microbiota (microscopic organisms) in the gut and the activity of the immune system during skin cancer immunotherapy.

Full description

Details will be available upon publication.

Enrollment: 54 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ≥18 years of age.
• Diagnosis of skin cancer.
• Planning to initiate or already on ANY type of immunotherapy.
• Able to provide urine and stool specimens.

Exclusion criteria

• Bowel resection.
• Major GI surgery in the past 5 years other than cholecystectomy and appendectomy.