HP Improves Sleep and Overall Survival Rate in Maintenance Hemodialysis Patients

Shanghai Pudong Hospital

Status: Completed

Conditions: Hemoperfusion

Treatments: Device: hemoperfusion(HP)

Study type: Interventional

Funder types: Other

Identifiers

NCT03487146

ShanghaiPudongH1

Details and patient eligibility

About

Sleep disturbance has been long-standing torments in most of patients with maintenance hemodialysis (HD). In this study, we attempted to explore whether long-term hemoperfusion (HP) could improve sleep disorder and increase overall survival rate in HD patients.

Enrollment: 156 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

1. duration of maintenance HD should be equal or more than 3 months,

2. patient's age should be equal or more than 18 years

   Exclusion Criteria:

   • i) he/she diagnosed with malignant tumors, an active rheumatism, infectious diseases, or a severe heart failure ii) he/she would disagree with the study

3. he/she has received a short-term poor prognosis

4. he/she would be more than 80 years old

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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156 participants in 2 patient groups

HD(hemodialysis) group

No Intervention group

Description:

HD group as conventional control arm

HD+HP(hemodialysis+hemoperfusion) group

Active Comparator group

Description:

HD+HP as active interventional group.HP was performed 1-2 times/per 2 weeks, and each session lasted for two hours.

Treatment:

Device: hemoperfusion(HP)