Human Albumin and Anastomotic Leakage After Gastric Cancer Surgery

Shanghai Jiao Tong University

Status: Completed

Conditions: Gastric Cancer; Anastomotic Leak

Treatments: Biological: Human albumin

Study type: Observational

Funder types: Other

Identifiers

NCT04490668

RJ-GC-Postop-complication 3

Details and patient eligibility

About

We investigate whether the intravenously administered human albumin is beneficial to prevent anastomotic leakage after gastric cancer surgery.

Full description

Anastomotic leakage after gastric cancer surgery is not very common but it is a very critical postoperative complication. Anastomotic leakage severely compromises the recovery after surgery. It increases the overall burden of patients and hospital resources. Postoperative mortality is higher in patients with anastomotic leakage.

Human albumin is routinely administered after surgery with a unproven hypothesis that the human albumin is beneficial to prevent anastomotic leakage. We investigate whether the intravenously administered human albumin is beneficial to prevent anastomotic leakage after gastric cancer surgery.

Enrollment: 1,049 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Histologically confirmed gastric cancer
• Patients who underwent radical gastrectomy

Exclusion criteria

• Patient who did not undergo gastrectomy

Trial design

1,049 participants in 2 patient groups

Human albumin support

Description:

Patients who received intravenous human albumin after gastric cancer surgery

Treatment:

Biological: Human albumin

No human albumin support

Description:

Patients who did not receive intravenous human albumin after gastric cancer surgery

Treatment:

Biological: Human albumin