Human Gut Microbiota and microRNA Expression

Air Force Military Medical University of People's Liberation Army

Status: Unknown

Conditions: Gut Microbiota; microRNA

Treatments: Dietary Supplement: stachyose; Dietary Supplement: Maltodextrin

Study type: Interventional

Funder types: Other

Identifiers

NCT05392348

KY20212094-C-1

Details and patient eligibility

About

In this study, stachyose was used as an intervention factor. We will evaluate changes in fecal gut microbiota and miRNA expression profiles in subjects under stachyose intervention

Full description

In the stachyose intervention group, each person in the stachyose intervention group took 5 g of stachyose daily before breakfast, and the administration method was 100 ml of drinking water dissolved and taken orally for two months. Each person in the placebo control group took the same amount of maltodextrin daily. Stool samples of the subjects were collected weekly.

Enrollment: 36 estimated patients

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy human

Exclusion criteria

• people who need intake antibiotics，probiotics or its product

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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36 participants in 2 patient groups, including a placebo group

Normal Control group

Placebo Comparator group

Description:

Subjects with maltodextrin as intervention，5g/kg·bw/day.

Treatment:

Dietary Supplement: Maltodextrin

Stachyose intervention group

Experimental group

Description:

Subjects with stachyose as intervention，5g/kg·bw/day.

Treatment:

Dietary Supplement: stachyose