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Human Metabolic Dynamics at Rest and During Aerobic Exercise Under Normobaric Normoxic and Moderate Hypoxic Conditions

B

Benjamin Gollasch

Status

Completed

Conditions

Energy Metabolism
Metabolism and Nutrition Disorder
Hypoxia

Treatments

Other: Hypoxia
Behavioral: 30-minute movement activity

Study type

Interventional

Funder types

Other

Identifiers

NCT03121885
MetaboDyn

Details and patient eligibility

About

The aim is to define in detail metabolic pathways at rest and during aerobic exercise in normal and healthy men and women under normobaric normoxic and moderate hypoxic conditions, using metabolomics technologies based on minimally invasive sampling relying on gas chromatography and mass spectrometry.

Enrollment

25 patients

Sex

All

Ages

18 to 75 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • approval and written, informed consent
  • healthy adults of varying fitness levels (age >18 years to 75 years)

Exclusion criteria

  • chronic illness requiring any medication
  • pregnancy
  • limitations regarding functioning in the hypoxic chamber
  • inability to follow simple instructions
  • relevant or severe abnormalities in medical history, physical examination, ECG routine laboratory parameters from blood and urine

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Double Blind

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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