Human Microbiome and Healthcare Associated Infections - Nursing Home Dwelling Older Veterans

University of Maryland Baltimore (UMB) logo

University of Maryland Baltimore (UMB)

Status and phase

Completed
Phase 4

Conditions

Human Microbiome

Treatments

Drug: Intranasal Mupirocin and Topical Chlorhexidine

Study type

Interventional

Funder types

Other
Other U.S. Federal agency

Identifiers

NCT04218799
HP-00058923

Details and patient eligibility

About

The purpose of the research is to find out the effect of commonly used topical antibiotics on the bacteria that live in the nose, throat and on the skin of older adults. In addition, the investigators want to determine if these topical antibiotics affect how bacteria are spread in Community Living Centers of the VA Maryland Health Care System.

Enrollment

19 patients

Sex

All

Ages

50+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Age 50 years or older.
  • Living in a participating nursing home for at least 80% of the past 3 months-
  • Willing to provide anterior nares, posterior pharynx, skin and throat specimens over the study period.
  • Willing to use intranasal mupirocin and topical chlorhexidine over a five day period.
  • Provide signed and dated informed consent from subject or LAR.

Exclusion criteria

  • Recent history of MRSA colonization
  • Use of mupirocin nasal ointment in past 3 months
  • Use of topical chlorhexidine in past 3 months
  • History of an allergic reaction to chlorhexidine or mupirocin

Trial design

Primary purpose

Health Services Research

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

19 participants in 1 patient group

Intranasal Mupirocin and Topical Chlorhexidine
Experimental group
Treatment:
Drug: Intranasal Mupirocin and Topical Chlorhexidine

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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