Human Papillomavirus Anal Infection (PAPILLAN)

Centre Hospitalier Universitaire de Besancon

Status: Completed

Conditions: HPV Infection

Treatments: Procedure: HPV detection in anal canal samples

Study type: Interventional

Funder types: Other

Identifiers

NCT02862795

API/2012/34

Details and patient eligibility

About

Human papillomavirus (HPV) are involved in up to 95 % of anal canal neoplastic lesions. Little is known about HPV carriage in anal canal previous to cancer occurrence in the population and pre-neoplastic lesions, and their risk factors. PAPILLAN is a prospective study that aims to study HPV infection (HPV low grade and high grade genotypes) prevalence in anal canal in a population non selected by its HIV status. In that purpose patients are prospectively recruited in a french university hospital gastroenterology unit and anal smears are collected during a colonoscopy with cytobrush.

Enrollment: 500 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients > 18 years
• patients undergoing colonoscopy under general anesthesia for any purpose
• signed written consent

Exclusion criteria

• age under 18
• Absence of written consent.
• patients incapable of giving consent

Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

500 participants in 1 patient group

HPV detection in anal canal samples

Other group

Treatment:

Procedure: HPV detection in anal canal samples