Human Papillomavirus (HPV) Infection in Pregnancy

University of Pennsylvania

Status: Completed

Conditions: Pregnancy Complications; Papillomavirus Infections

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT00194311

801452

R01HD042100-15 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The purpose of this study is to determine if maternal infection with human papillomavirus (HPV) is associated with pregnancy complications including spontaneous preterm delivery (sPTD), severe preeclampsia (PE), and poor fetal growth.

Enrollment: 620 estimated patients

Sex: Female

Ages: 13 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• All women presenting for prenatal care at the Hospital of the University of Pennsylvania or affiliated clinics

Exclusion criteria

• Multiple gestations
• Medical conditions such as diabetes, chronic hypertension, renal disease
• Fetal malformations or chromosomal anomalies
• Fetal death

Trial design

620 participants in 1 patient group

pregnancy complications

Description:

prospective cohort study is to determine if maternal infection with Human papillomavirus (HPV) is associated with pregnancy complications including spontaneous preterm delivery (sPTD), severe preeclampsia (PE) (as per current ACOG: American College of Obstetrics and Gynecology criteria), and intrauterine growth restriction (IUGR).