HUTT to Assess Cardiac Autonomic Nervous Function

Hebei Medical University

Status: Enrolling

Conditions: Autonomic Nervous System Diseases

Study type: Observational

Funder types: Other

Identifiers

NCT06236945

20230213

Details and patient eligibility

About

Autonomic nervous system diseases can cause abnormalities in the circulatory system, leading to malignant arrhythmia and sudden cardiac death. Standardized, operable, and simplified diagnostic indicators are urgently needed to evaluate autonomic nervous function, particularly cardiac autonomic nervous function. The investigators use HUTT in order to provide data support for cardiac autonomic nervous system evaluation.

Full description

In this study, 169 samples with vertical tilt test and 24-h Holter ECG data from February 13, 2023 to October 31, 2023 were selected. The AC, DC, and 24-h HRV were compared with the CASS to identify the indicators with the strongest correlation with the CASS sympathetic and vagus nerve scores. The best index was selected, and the score intervals were delimited. The sensitivity and specificity of the defined vagal and sympathetic intervals were analyzed.

Enrollment: 1,122 estimated patients

Sex: All

Ages: 12 to 85 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Vertical tilt test and 24-hour holter electrocardiogram were performed at the same time

  • Receive treatment in our hospital.

Exclusion criteria

• Taking benzodiazepines or hypotensive drugs within 24 hours

  • Combined with mental illness, severe dementia, serious organ disease

    • Severe arrhythmia, deep breathing and poor coordination of Valsaval movements affected the interpretation of results.