Hyaluronan in Embryo Transfer Media

Peter Fancsovits, Ph.D.

Status: Completed

Conditions: Infertility

Study type: Observational

Funder types: Other

Identifiers

NCT02077608

SemmelweisU-002

Details and patient eligibility

About

Prospective randomized double blind comparison of hyaluronan enriched embryotransfer media and conventional embryotransfer media in human IVF treatments. Embryos selected for transfer are incubated in a culture media containing high concentration of hyaluronan or low concentration of hyaluronan.

Primary outcome: implantation and pregnancy rates

Enrollment: 580 patients

Sex: Female

Ages: 18 to 48 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Infertile patients
• entering in vitro fertilization treatment
• at least 1 embryo transferred

Exclusion criteria

• IVF treatment with donated oocytes
• No embryo available for transfer

Trial design

580 participants in 2 patient groups

Hyaluronan enriched transfer media

Description:

Embryos are incubated at least 10 minutes in hyaluronan enriched embryo transfer media before transfer

Control group

Description:

Embryos are incubated in embryo transfer media containing low concentration of hyaluronan for at least 10 minutes before transfer