Hyaluronic Acid Delivery: CO2 Laser Versus Thulium Laser Treatment

Universitätsklinikum Hamburg-Eppendorf

Status: Enrolling

Conditions: Aging Skin

Treatments: Other: CO2 laser + HA; Other: Thulium laser + HA

Study type: Interventional

Funder types: Other

Identifiers

NCT06431282

01-24

Details and patient eligibility

About

• Weakly crossed-linked hyaluronic acid (HA) can be delivered through multiple injections into the dermal and subnormal layer to improve skin quality. However, this treatment comes with multiple bumps for several days.
• Alternatively, HA can be delivered after CO2 laser or thulium laser pretreatment. As microscopic analysis after this treatment is limited, the object of the present study is to investigate the morphological cellular changes after CO2 laser and thulium laser delivered HA into human skin.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy male and female patients

Exclusion criteria

• pregnancy, breast feeding
• open wounds at the area to be treated

Trial design

Primary purpose: Other

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 2 patient groups

CO2 laser + HA

Active Comparator group

Description:

Probands are treated with a CO2 laser. Afterwards a HA gel will be applied.

Treatment:

Other: CO2 laser + HA

Thulium laser + HA

Active Comparator group

Description:

Probands are treated with a thulium laser. Afterwards a HA gel will be applied.

Treatment:

Other: Thulium laser + HA