Hyaluronic Acid Mouthwash as Adjunct

Cairo University (CU)

Status and phase: Completed; Phase 3

Conditions: Gingivitis; Chronic

Treatments: Drug: Hyaluoric acid mouthwash; Drug: Chlorhexidine 0,12%

Study type: Interventional

Funder types: Other

Identifiers

NCT07366398

ACU-Per2

Details and patient eligibility

About

Patients were instructed to use 2 different mouthwashes after performing professional tooth cleaning. The effect of each of the 2 mouthwashes was detected.

Full description

The study tests the efficacy of hyaluronic acid (HYL) mouthwash as adjunct to Chlorhexidine (CHX) mouthwash compared to Chlorhexidine mouthwash only in 16 gingivitis patients. Patients were randomly assigned to either control group received (Chlorhexidine mouthwash) or test group received (hyaluronic acid + Chlorhexidine mouthwash). Clinical parameters and patient reported outcomes as post-operative questionnaire were assessed at baseline and seven days post-operatively.

Enrollment: 16 patients

Sex: All

Ages: 25+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed with gingivitis

Exclusion criteria

• pregnant or lactating females and current smokers

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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16 participants in 2 patient groups

Chlorhexidine mouthwash

Active Comparator group

Treatment:

Drug: Chlorhexidine 0,12%

Hyaluronic acid + Chlorhexidine mouthwash

Active Comparator group

Treatment:

Drug: Chlorhexidine 0,12%

Drug: Hyaluoric acid mouthwash