Hyaluronic Acid With Scaling & Root Planing In Chronic Periodontitis Patients With Diabetes Mellitus Type 2

Cairo University (CU)

Status: Completed

Conditions: Chronic Periodontitis

Treatments: Procedure: Periodontal treatment with Hyaluronic acid associated with SRP; Procedure: Scaling & root planning alone

Study type: Interventional

Funder types: Other

Identifiers

NCT03807596

15062011

Details and patient eligibility

About

The present study aimed to assess the adjunctive use of Hyaluronic acid with scaling & root planing (SRP) in patients with chronic periodontitis & diabetes mellitus type 2.

Full description

Thirty subjects with chronic periodontitis & diabetes mellitus type 2 were included in this randomized clinical trial. These subjects were randomly allocated into test & control equal groups. The test group comprised fifteen patients who received SRP with subgingival application of Hyaluronic acid as an adjunct. The control group included fifteen patients who received SRP alone. Plaque index (PI), gingival index (GI), probing depth (PD) & clinical attachment level (CAL) were measured & documented at baseline, 6 weeks & 12 weeks intervals.

Enrollment: 30 patients

Sex: All

Ages: 38 to 56 months old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with chronic periodontitis and type 2 diabetes mellitus
• Minimum of 20 teeth
• Clinical attachment level (CAL) ≥ 3 mm
• Probing depth (PD) ≥ 4 mm.

Exclusion criteria

• Pregnant females
• Smokers

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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30 participants in 2 patient groups

SRP group

Active Comparator group

Description:

Chronic periodontitis patients with type 2 diabetes mellitus recieved Periodontal treatment in the form of scaling \& root planing (SRP) alone.

Treatment:

Procedure: Scaling & root planning alone

Hyaluronic acid & SRP group

Experimental group

Description:

Chronic periodontitis \& type 2 diabetes mellitus patients received Periodontal treatment in the form of scaling \& root planing (SRP) with the adjunctive use of hyaluronic acid.

Treatment:

Procedure: Periodontal treatment with Hyaluronic acid associated with SRP