Hybrid Intraprocedural Imaging Based on 2 Different Imaging Methods

RWTH Aachen University

Status: Withdrawn

Conditions: Left Ventricular Wall Motion Abnormalities; Angina Pectoris

Treatments: Procedure: 2D-strain echo

Study type: Interventional

Funder types: Other

Identifiers

NCT01389674

CTC-A 08-001

EK 079/10

HIB-Study

Details and patient eligibility

About

The investigators will check the feasibility of an intraprocedural vitality diagnostics and the identification of an indication for Percutaneous transluminal coronary angioplasty (PTCA).

Full description

After myocard vitality diagnostics with MRI patients will underwent additionally an stress echocardiography within the exploration. By this ultrasound we will measure the LV mass and the ejection fraction per apical 2-, 3- and 4-chamber view.

In addition a 2D-strain-analysis will be done to measure the systolic and diastolic strain and also the circumferential and radial strain rate parameter (by depicting three parasternal short axis views in the basal, mid-ventricular and apical plane).

These measurements will be compared with the studies-conditioned MRI-finding (as reference) to find the optimal strain-parameter and the optimal cut-off-data for an intraprocedural vitality diagnostics of the single layers (endocardial, myocardial, and epicardial) for this patient group.

The data upraised through this are compared off-line to the MRI findings.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• left ventricular wall motion abnormalities
• existent myocardial vitality MRI exploration
• reduced LV-function
• steady angina pectoris
• patients which are legally competent and which are mentally able to understand the study staff
• patients give their written consent

Exclusion criteria

• pregnancy or lactation
• acute or instable angina pectoris
• acute myocardial infraction in the last 3 month

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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0 participants in 1 patient group

2D-strain echo

Experimental group

Description:

After myocard vitality diagnostics with MRI follows a stress echocardiography to determine the LV volumes and EF. The received Data are compare with the MRI-Data(reference)to identify the ideal strain-parameters and Cut-Off-Result for an intraprocedural vitality diagnostic of the different films (endocardial, myocardial and epicardial).

Treatment:

Procedure: 2D-strain echo