Hydrodissection as a Treatment for Carpal Tunnel Syndrome

Mayo Clinic

Status

Completed

Conditions

Carpal Tunnel Syndrome

Treatments

Procedure: Hydrodissection

Procedure: Regular Injection

Study type

Interventional

Funder types

Other

Identifiers

NCT03427983

17-009840

Details and patient eligibility

About

This is a pilot study designed to acquire data on the added value of hydrodissection when using a corticosteroid injection as a treatment for patients with carpal tunnel syndrome. Hydrodissection is part of a standard clinical care injection under ultrasound guidance in which the fluid is used to separate the nerve from surrounding structures.

Enrollment

20 patients

Sex

All

Ages

21 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Clinical CTS diagnosis with indication for steroid injection as determined by attending physician (if both hands are involved, only the side with the most severe CTS as indicated by electromyography (EMG) will be included) AND
adult men and women between age 21 and 80 AND
no more than moderate severity as indicated by EMG AND
symptoms of numbness or tingling for at least 4 weeks in the median nerve distribution area AND
classic or probable carpal tunnel syndrome on Katz-Stirrat hand diagram AND
ability to complete English-language questionnaires and clinical evaluations AND
is reachable by phone for the follow up contact

Exclusion criteria

Exclusion criteria are largely based on the premises of only including patients with idiopathic carpal tunnel syndrome without expected interferences of the acquisition of the ultrasound images or corticosteroid treatment.

Previous Carpal Tunnel Release (CTR) or other volar wrist surgery on the study hand OR known tumor/mass OR deformity of the study hand/wrist OR
previous history of steroid injection into carpal tunnel OR
currently taking a steroid medication either regularly or on an as needed basis OR
any of the following clinical diagnoses or conditions: Cervical radiculopathy; rheumatoid or other inflammatory arthritis, including gout; osteoarthritis in the wrist; renal failure; sarcoidosis; peripheral nerve disease; diabetes, thyroid disease or other metabolic disorder; pregnancy; amyloidosis; or major trauma (fractures or complete ligamentous tears) to the ipsilateral arm OR
prisoners, institutionalized individuals, or others who may be considered vulnerable populations, such as individuals with dementia