Hydrogen Inhalation for Health and Exercise Performance (HIHEP)

University of Novi Sad, Faculty of Sport and Physical Education

Status: Completed

Conditions: Exercise Performance

Treatments: Other: Placebo; Other: Hydrogen

Study type: Interventional

Funder types: Other

Identifiers

NCT03846141

UniversityNSFSandPE

Details and patient eligibility

About

In this randomized double-blind, placebo-controlled, crossover pilot trial, we evaluated the effects of 7-day H2 inhalation on exercise performance outcomes and serum hormonal and inflammation profiles in a cohort of young men and women.

Full description

All participants were allocated to receive either gaseous hydrogen (4%) or placebo (room air) by 20-min once-per-day inhalation for 7 days, with wash-out period of 7 days to prevent the residual effects of interventions across study periods. The primary treatment outcome was the change in running time-to-exhaustion from baseline to day 7. Additionally, assessment of other exercise performance endpoints and clinical chemistry biomarkers were performed at baseline and after 7 days after each intervention.

Enrollment: 20 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Age ≥ 18 -35 years Body mass index 20 - 25 kg/m2 Free of major diseases Physically active Must be able to give written informed consent

Exclusion criteria

Use of any dietary supplements within 4 weeks before study commences Abnormal values for lab clinical chemistry (> 2 SD)

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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20 participants in 2 patient groups, including a placebo group

Placebo

Placebo Comparator group

Description:

Room air for inhalation

Treatment:

Other: Placebo

Hydrogen

Experimental group

Description:

Hydrogen (4%) for inhalation

Treatment:

Other: Hydrogen