Hydroxypropyl-methylcellulose and GlicoPro® Eyedrops in the Treatment of Dry Eye Disease: Clinical Study

University of Milan

Status and phase

Completed

Phase 4

Conditions

Dry Eye

Treatments

Device: Hydroxypropyl-methylcellulose

Device: HPMC+GlicoPro eyedrops

Study type

Interventional

Funder types

Other

Identifiers

NCT06726525

Prot. 20-22

Details and patient eligibility

About

The goal of this clinical trial is to learn if Hydroxypropyl-methylcellulose and GlicoPro® eyedrops work to treat mild-to-moderate dry eye disease in adult patients. The main questions it aims to answer are:

Do Hydroxypropyl-methylcellulose and GlicoPro® eyedrops reduce patients' symptoms? Do Hydroxypropyl-methylcellulose and GlicoPro® eyedrops increase patients' tear film stability? Researchers will compare Hydroxypropyl-methylcellulose and GlicoPro® eyedrops to Hydroxypropyl-methylcellulose without GlicoPro® eyedrops to see if Hydroxypropyl-methylcellulose and GlicoPro® formulation works better to treat dry eye..

Participants will

Take Hydroxypropyl-methylcellulose and GlicoPro® eyedrops or Hydroxypropyl-methylcellulose eyedrops every day for 3 months
Visit the clinic 3 times in 3 months for checkups and tests

Enrollment

44 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age >18 years
Ocular Surface Disease Index (OSDI) >12 AND <65
Fluorescein breakup time (FBUT) <10 seconds OR (Oxford staining Score >1 AND <4).

Exclusion criteria

Systemic or ocular diseases with known effect on tear film and ocular surface
Systemic or ocular medications with known effect on tear film and ocular surface
Contact lens wearing,
Ocular surgery in the 12 months before enrollment
Known allergy or poor tolerance to any ingredient of the study products
Presumed poor compliance to study procedures.