Hydroxypropylmethylcellulose 0.3% and Sodium Hyaluronate 0.18% for Ocular Surface Disease in Glaucoma

Mahidol University

Status: Unknown

Conditions: Glaucoma; Ocular Surface Disease

Treatments: Drug: sodium hyaluronate; Drug: hydroxypropylmethylcellulose

Study type: Interventional

Funder types: Other

Identifiers

NCT01284439

655/2553(EC4)

Details and patient eligibility

About

To study effect of hydroxypropylmethylcellulose 0.3% and sodium hyaluronate 0.18% in the treatment of ocular surface disease in glaucoma patients.

Enrollment: 120 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• OSDI > or equal 20 and eye lid inflammation , meibomian gland inflammation,conjunctival injection,follicle at tarsus , positive corneal staining , tear break up time less than 8 seconds , tear volume less than 5.5 mm.

Exclusion criteria

• Age below 18 yo
• Active infectious corneal disease
• Post penetrating keratoplasty or glaucoma drainage device
• Known allergy to medication
• Lactation , Pregnant

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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120 participants in 2 patient groups

TearA

Experimental group

Treatment:

Drug: hydroxypropylmethylcellulose

TearB

Experimental group

Treatment:

Drug: sodium hyaluronate