Hyperbaric Oxygen Therapy and SPECT Brain Imaging in Traumatic Brain Injury

Paul G. Harch, M.D.

Status and phase: Unknown; Phase 1

Conditions: Residual Neurological, Cognitive, Emotional, Behavioral Effects From Traumatic Brain Injury

Treatments: Drug: Hyperbaric oxygen therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT00594503

LSU IRB #6625

Details and patient eligibility

About

Hypothesis: That SPECT brain imaging tracks and is consistent with clinical improvements in patients receiving hyperbaric oxygen therapy (HBOT) for chronic traumatic brain injury.

Full description

The study is a retrospective chart review of patients with chronic neurological, emotional, social, and cognitive deficits from mild, moderate, or severe traumatic brain injury who underwent SPECT brain imaging as part of their evaluation and treatment with hyperbaric oxygen therapy in my practice over the last two decades. The purpose of the study is to see if the functional imaging is consistent with the clinical and cognitive testing.

Enrollment: 45 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults or children with traumatic brain injury at least one year old

Exclusion criteria

• None

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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45 participants in 1 patient group

Hyperbaric oxygen therapy-TBI

Experimental group

Description:

Low pressure hyperbaric oxygen therapy

Treatment:

Drug: Hyperbaric oxygen therapy