Hyperbaric Oxygen Therapy Combined With Polarized Light Therapy Effect on Neuropathic Foot Ulcer

Al-Zaytoonah University of Jordan

Status: Enrolling

Conditions: Neuropathic Diabetic Ulcer - Foot

Treatments: Other: traditional treatment; Other: Hyperbaric oxygen therapy combined with polarized light therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT06889038

Hyperbaric oxygen therapy

Details and patient eligibility

About

Neuropathic ulcers develop due to nerve damage (neuropathy), commonly seen in conditions like diabetes, leading to loss of sensation, repetitive trauma, and poor wound healing. These ulcers typically occur on weight-bearing areas, hyperbaric oxygen and polarized light therapies may have a synergistic effect, improving oxygenation, cellular activity, and overall healing outcomes in neuropathic ulcers, particularly in diabetic foot ulcers.

Enrollment: 40 estimated patients

Sex: All

Ages: 55 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients had cardiac ejection fraction (CEF) 50%
• blood pressure (BP) 150/90mmHg.
• Chest X-ray was reported normal
• all patients were clinically evaluated by a specialized ear, nose, and throat (ENT) physician to ensure suitability for the hyperbaric chamber.

Exclusion criteria

• chronic obstructive pulmonary disease, malignancy
• cardiac pacemakers, or any disorder that lead to ulcers other than diabetes
• chronic peripheral arterial disease.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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40 participants in 2 patient groups

study group

Experimental group

Description:

patients will evaluated to be fit for HBO therapy to ensure cardiac ejection fraction over 50% and chest CT to ensure chest free from any pathology

Treatment:

Other: Hyperbaric oxygen therapy combined with polarized light therapy

control

Active Comparator group

Description:

topical medication

Treatment:

Other: traditional treatment