Hyperbaric Oxygen Therapy (HBOT) as a Treatment for COVID-19 (COVID-19) Infection

Ochsner Health System

Status: Withdrawn

Conditions: COVID-19

Treatments: Device: Hyperbaric Oxygen Therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT04343183

STUDY00001051

Details and patient eligibility

About

Patients who meet inclusion criteria will be randomized into treatment vs control group. Treatment groups will undergo Hyperbaric Oxygen Therapy (HBOT) and compared to the control group.

Full description

After enrollment, patients will be randomized into treatment vs control group. Both populations will receive the same inpatient medical treatment. All patients in the treatment group will undergo hyperbaric oxygen therapy under the same treatment protocol. After completion of the treatment protocol, specific study endpoints will be compared between the treatment and control groups.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult inpatients >18 years old
• Positive PCR COVID-19 testing
• CT evidence of interstitial opacity
• Oxygen saturation <90% on room air
• pO2 = 55-70.

Exclusion criteria

• Increased oxygen requirements
• Hemodynamic instability (MAP<65)
• Bradycardia (HR<50)
• History of seizure disorder
• Pneumothorax
• GFR<30
• Hemodialysis
• Refractory anxiety/claustrophobia
• Current pregnancy
• Uncorrectable hypoglycemia

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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0 participants in 2 patient groups

HBOT treatment group

Active Comparator group

Description:

Patients will receive hyperbaric oxygen therapy

Treatment:

Device: Hyperbaric Oxygen Therapy

Standard of Care group

No Intervention group

Description:

Patients will not receive hyperbaric oxygen therapy and will receive the current standardized treatment protocol