Hypercapnia During Shoulder Arthroscopy

Gachon University Gil Medical Center

Status: Completed

Conditions: Cerebral Ischemia

Treatments: Behavioral: hypercapnia; Behavioral: normocapnia

Study type: Interventional

Funder types: Other

Identifiers

NCT02643030

GIRBA2674-2012

Details and patient eligibility

About

The purpose of this study is to evaluate the effects of hypercapnia on hemodynamics and cerebral oxygenation during shoulder arthroscopy.

Full description

The patients are randomly allocated to receive normocapnia or hypercapnia . After the 70º sitting position, record the mean arterial pressure (MAP), heart rate, and regional oxygen saturation (rSO2).

Enrollment: 40 patients

Sex: All

Ages: 20 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients undergoing elective shoulder arthroscopic surgery

Exclusion criteria

• a history of age > 65 years, morbidly obesity (BMI > 30 kg/m2), diffuse lung disease, uncontrolled systemic hypertension, intracranial disease, cardiovascular and cerebrovascular disease.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

normocapnia

Experimental group

Description:

Tidal volume (10 ml/kg) and respiratory rate is adjusted to achieve the objective values of ETCO2 35mmHg

Treatment:

Behavioral: normocapnia

hypercapnia

Active Comparator group

Description:

Tidal volume (6ml/kg) and respiratory rate is adjusted to achieve the objective values of ETCO2 45mmHg

Treatment:

Behavioral: hypercapnia