Hyperglycemic Response and Steroid Administration After Surgery (DexGlySurgery)

Centre Hospitalier Universitaire de Nīmes

Status: Completed

Conditions: Healthy; Diabetes

Treatments: Drug: Steroid Drug

Study type: Observational

Funder types: Other

Identifiers

NCT03390179

CHUNimes

Details and patient eligibility

About

The hyperglycemic response to surgery and the added effect of low-dose steroids (dexamethasone 4 to 8mg), and whether these differ in diabetics and nondiabetics remain unclear. Therefore, we prospectively evaluate the intraoperative and postoperative serum glucose concentrations in diabetics and nondiabetics that received intravenous steroid administration. This multicentre study include > 250 patients.Primary endpoiunt was glucose concentration at H6 after surgery. Secondary endpoints were glucose concentration at H12 and at H24 and effect of anesthesia (regional anesthesia)

Enrollment: 250 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• elective surgery under anesthesia

Exclusion criteria

• < 50 kg
• emergency
• insulin therapy
• cardiac surgery
• refusal
• hyperglycemia> 2g/L

Trial design

250 participants in 2 patient groups

diabetes

Description:

Patient with non insulin diabetes

Treatment:

Drug: Steroid Drug

control

Description:

Patient without diabete

Treatment:

Drug: Steroid Drug