Hyperopic LASIK With Crosslinking Versus Standard LASIK

Minia University

Status: Completed

Conditions: Hyperopia

Treatments: Procedure: LASIK

Study type: Interventional

Funder types: Other

Identifiers

NCT03224013

Hyperopic LASIK

Details and patient eligibility

About

Analysis corneal and refractive stability of hyperopic laser-assisted in situ keratomileusis (LASIK) with and without concurrent prophylactic high-fluence cross-linking (CXL).

Full description

Interventional prospective consecutive comparative case control series of cases; 50 eyes of 25 patients with mean age 35.7 ± 12.4 (Range 18-61years) with hyperopia or hyperopic astigmatism underwent customized LASIK with concurrent prophylactic high-fluence cross-linking in right eye (group 1) and customized LASIK only in left eye (group 2). Cases with hyperopia +1 diopter to +6 diopters or hyperopic astigmatism up to 4 diopters were included in the study. Patients with previous intraocular or corneal surgery, active corneal disease were excluded from the study.

Main outcome measures were uncorrected visual acuity (UCVA), manifest refractive spherical equivalent (MRSE), cycloplegic refractive spherical equivalent (CRSE), keratometric measurements and spherical aberrations at 4 mm and maximum pupil and their evolution along 6 months postoperatively.

Enrollment: 25 patients

Sex: All

Ages: 18 to 61 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Cases with hyperopia +1diopter to +6 diopters or hyperopic astigmatism up to 4 diopters

Exclusion criteria

• Patients with previous intraocular or corneal surgery, active corneal disease

Trial design

Primary purpose: Other

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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25 participants in 2 patient groups

Hyperopic LASIK with crosslinking

Active Comparator group

Description:

group 1:hyperopic customized LASIK with concurrent prophylactic high-fluence cross-linking

Treatment:

Procedure: LASIK

Hyperopic LASIK only

Active Comparator group

Description:

group 2: hyperopic customized LASIK only

Treatment:

Procedure: LASIK