Hyperpolarized 129Xe MRI Lung Health Cohort (XeLHC)

University of Kansas

Status: Enrolling

Conditions: Healthy

Treatments: Drug: Hyperpolarized Xe129

Study type: Observational

Funder types: Other

Identifiers

NCT05766384

STUDY00160099

Details and patient eligibility

About

A subset of young adults participating in the American Lung Association (ALA) Lung Health Cohort (LHC) will be imaged using Hyperpolarized 129Xe MRI to assess lung structure and function. Images will be used to improve the understanding of lung health and early lung abnormalities that may lead to chronic lung disease.

Enrollment: 260 estimated patients

Sex: All

Ages: 25 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Is enrolled in the American Lung Association Lung Health Cohort Study.
• Has completed CT imaging for the LHC study within 2 years of the scheduled Xe-MRI date.

Exclusion criteria

• Pacemaker, internal defibrillator or other implanted electronic devices or any standard MRI contraindications (e.g., claustrophobia, > 140 cm shoulder circumference, dependent on weight distribution).
• Is pregnant or breastfeeding
• Oxygen saturation (SpO2) <88% on room air or with supplemental oxygen.