Hypertensive Disorders of Pregnancy in Adolescence and Primipaternity

Saint Thomas Hospital (HST)

Status: Unknown

Conditions: Preeclampsia

Study type: Observational

Funder types: Other

Identifiers

NCT01374477

MHST2011-05

Details and patient eligibility

About

Hypertensive disorders of pregnancy are one of the most frequent complications of pregnancy, being a serious health problem around the world.

Previous studies have suggested that there is an association between a short period of exposure to paternal sperm of a new sexual partner and the development of an immunological reaction that could trigger a hypertensive disorder of pregnancy. For this reason we want to study the relationship between the primipaternity concept (exposure to male antigens present in semen over a short period of time previous to the pregnancy) and the development of preeclampsia in adolescents.

Enrollment: 110 estimated patients

Sex: Female

Ages: Under 19 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 19 year old or less
• Pregnancy > 24 weeks at the moment of delivery

Exclusion criteria

• 20 years old or more.
• Pregnancy < 24 weeks at the moment of delivery

Trial design

110 participants in 2 patient groups

Adolescent with preeclampsia

Description:

Patients \< 19 years old who delivered in our institution (vaginal birth or cesarean) that developed a hypertensive disorder of pregnancy.

Normal adolescent

Description:

Patients \< 19 years old who delivered in our institution (vaginal birth or cesarean) without developing a hypertensive disorder of pregnancy.