Hypertonic Solution in Off Pump Coronary Artery Bypass Graft Surgery

Hospital Pitangueiras

Status and phase: Unknown; Phase 4

Conditions: Coronary Artery Disease

Treatments: Drug: Hypertonic solution; Drug: Isotonic

Study type: Interventional

Funder types: Other

Identifiers

NCT01463917

hypertonic off pump CABS

Details and patient eligibility

About

This is a comparison between Hypertonic versus isotonic solution in a double blind randomized trial for off pump Coronary Artery Bypass Graft (CABG) surgery targeting the left marginal branch.

Hypertonic solution should provide better tolerance for heart mobilization with less volume expansion and less drugs.

Enrollment: 20 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Off pump CABG targeting the left marginal branch

Exclusion criteria

• On pump surgery

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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20 participants in 2 patient groups, including a placebo group

Hypertonic

Active Comparator group

Description:

Use of Hypertonic solution during left marginal branch CABG surgery.

Treatment:

Drug: Hypertonic solution

Isotonic

Placebo Comparator group

Description:

Use of Isotonic solution during left marginal branch CABG surgery.

Treatment:

Drug: Isotonic