HYPNOsis in the Management of Atopic Dermatitis in Children and Teenagers (HypnoDA)

Centre Hospitalier Universitaire de la Réunion

Status: Enrolling

Conditions: Dermatitis

Treatments: Behavioral: Hypnosis

Study type: Interventional

Funder types: Other

Identifiers

NCT05611346

2022/CHU/15

Details and patient eligibility

About

Atopic dermatitis (AD) is a chronic inflammatory dermatosis, common in children. It causes pruritus and skin lesions that can have a significant impact on patients' quality of life. AD can be difficult to treat because of its chronicity, demanding local care, corticophobia and the financial cost of non-reimbursed products. Patients are often looking for therapeutic alternatives. Medical hypnosis is a therapeutic alternative via hypnoanalgesia induced by direct suggestions of comfort and skin soothing and via anxiolysis, by working on stress management and self-esteem reinforcement. Four studies are interested in its action in AD and seem to show a reduction in pruritus, skin pain, an improvement in the intensity of atopic dermatitis, sleep, mood and for some a cure of AD. These results are encouraging but limited by the absence of a control group or by the small population included. Therefore, we propose in a first step to evaluate the feasibility of an hypnosis program through a pilot study, designed in the miniature format of a future, larger scale, randomized controlled trial.

Enrollment: 32 estimated patients

Sex: All

Ages: 8 to 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Children aged 8 to 17 years
• Understanding french
• Have a clinical diagnosis of mild-to-severe AD with a SCORing Atopic Dermatitis (SCORAD)
• Referred by their referring physician in the Reunionese therapeutic education program for AD provided within the atopy school of the Reunion University Hospital. - Oral consent of the child and of one of the legal representatives collected.

Exclusion criteria

• Children refusing to participate in the hypnosis session
• Not having the possibility to listen to an audio file,
• Already practicing self-hypnosis for their AD before inclusion,
• Having a contraindication to hypnosis (psychiatric disorders, psychosis)
• Treated by a systemic treatment for their AD.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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32 participants in 2 patient groups

Therapeutic education program

No Intervention group

Therapeutic education program and Hypnosis

Experimental group

Treatment:

Behavioral: Hypnosis