Hypnosis and Virtual Reality in Bone Marrow Examination

Bnai Zion Medical Center

Status: Enrolling

Conditions: Hematologic Diseases

Treatments: Device: Hypnosis; Device: Virtual reality (VR)

Study type: Interventional

Funder types: Other

Identifiers

NCT05982249

0053-23-BNZ

Details and patient eligibility

About

The goal of this clinical trial is to compare the effects of hypnosis, virtual reality or their combination in patients undergoing a bone marrow procedure.

The main question it aims to answer is whether such interventions may relieve anxiety and other symptoms described by patients undergoing the procedure.

Before the bone marrow procedure and after being explained on the study and signing informed consent, the nurse will measure vital signs and participants will fill-out a 2-minutes' questionnaire and will be assigned to one of 3 groups:

• Hearing a 7-minutes hypnotic script via earphones
• Seeing and hearing virtual images and sounds via a virtual reality device during 7 minutes
• None of these After these interventions or 10 minutes after assignation for patients not receiving intervention, patients will fill questionnaires again (about 5 minutes for filling the 2 questionnaires) and vital signs will be measured again. Then the bone marrow procedure will be performed. After the bone marrow procedure, the participants will fill-out another 2-minutes questionnaire and vital signs will be measured by the nurse.

Researchers will compare hypnotic script, virtual reality, their combination or none of them to see if they can affect anxiety and other complaints in patients undergoing a bone marrow procedure.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age 18 or older
2. Candidate for a BM examination at the hematology unit
3. Ability to answer questionnaires in Hebrew, Arabic or Russian
4. Informed consent form signing

Exclusion criteria

1. Major hearing impairment
2. Major visual impairment.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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100 participants in 3 patient groups

Hypnosis (H)

Experimental group

Description:

Patients will be given earphones to hear a hypnotic script that was recorded by Dr. Zahi Arnon, a psychologist specializing in hypnosis after observing about ten bone marrow (BM) examinations at the hematology institute. The length of the recording is about 7 minutes.

Treatment:

Device: Hypnosis

Virtual reality (VR)

Experimental group

Description:

Patients will be connected to a VR device that will transmit to the patient's choice a 3D screen and soothing noise for about 7 minutes.

Treatment:

Device: Virtual reality (VR)

Control (C)

No Intervention group