Hypofractionated Radiotherapy for Lung Cancer
Status and phase
Conditions
Treatments
Study type
Funder types
Identifiers
Details and patient eligibility
About
The purpose of this trial is to pilot reducing the duration of radiation treatment for lung cancer patients from 6 to 5 weeks using tomotherapy. Specific patient doses will be based on tumor volume being treated. Modeling has shown that increased biologically effective dose (BED) to tumors can be achieved by shortening the radiation delivery schedule and increasing the dose per fraction. This requires decreasing the total dose to hold lung toxicity constant at each dose per fraction level. This is a major paradigm shift in the treatment in this disease and is projected to result in significant improvements in patient outcome as well as a substantial cost savings.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- Thoracic neoplasm requiring at lest 60 Gy conventional radiotherapy
Exclusion criteria
- Prior bleomycin or gemcitabine chemotherapy
- Prior thoracic radiotherapy
Trial design
Primary purpose
Allocation
Interventional model
Masking
79 participants in 5 patient groups
Trial contacts and locations
Loading...
Data sourced from clinicaltrials.gov
Clinical trials
Research sites
Resources
Legal