Hypomagnesemia and Its Clinical Outcome (Hypogamnesamia)

Bangladesh Bioscience Research Group

Status: Completed

Conditions: Critical Illness; Hypomagnesemia; Intensive Care Unit (ICU) Patients; Scoring Systems

Treatments: Diagnostic Test: No intervention (observational study)

Study type: Observational

Funder types: Other; NETWORK

Identifiers

NCT07089004

BBMH/2023/RP-2342

BBMH/June/2023/011 (Registry Identifier)

Details and patient eligibility

About

Magnesium is an essential electrolyte involved in numerous physiological processes, including maintaining cellular integrity, regulating muscle tone, supporting cardiovascular function, and modulating immune responses. Despite its critical role, magnesium is often overlooked in clinical practice, earning it the title of the "forgotten electrolyte." Hypomagnesemia, defined as serum magnesium levels below 1.5 mEq/L, has been associated with adverse clinical outcomes such as increased mortality, prolonged ICU stays, and higher requirements for mechanical ventilation. Critically ill patients are particularly vulnerable to hypomagnesemia due to various underlying conditions, gastrointestinal losses, and renal complications. However, limited data are available from Bangladesh on the burden and clinical impact of hypomagnesemia in ICU settings. This study aims to assess the correlation between hypomagnesemia and clinical outcomes, including length of ICU stay, need for mechanical ventilation, and mortality among critically ill patients in a tertiary care ICU in Bangladesh.

Enrollment: 112 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged 18 years and above.
• Patients admitted to the Intensive Care Unit (ICU).
• Patients who have serum magnesium levels measured within 24 hours of ICU admission.

Exclusion criteria

• Patients with known end-stage renal disease on dialysis.
• Patients with a history of magnesium supplementation prior to ICU admission.
• Pregnant women.
• Patients with incomplete medical records or unavailable laboratory data.