Hypotension Prediction Effect on AKI

Ewha Womans University

Status: Completed

Conditions: Bladder Cancer

Treatments: Device: BP management with HPI guidance

Study type: Interventional

Funder types: Other

Identifiers

NCT04994639

2021-06-002

Details and patient eligibility

About

It is a single-center randomized controlled trial that aims to figure out the effect of the hypotension prediction index (HPI) on the prevention of acute kidney injury (AKI) after radical cystectomy. The primary hypothesis is that HPI software guidance prevents postoperative AKI by reducing the duration and severity of intraoperative hypotension (IOH).

Enrollment: 120 patients

Sex: All

Ages: 19+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≧ 19
• Patients undergoing radical cystectomy with neobladder reconstruction
• Patients undergoing radical cystectomy with ileal conduit urinary diversion

Exclusion criteria

• Unable to voluntarily give consent
• Unable to use both radial arteries due to such reasons: prior surgery on the radial artery, breast cancer history with axillary LN dissection, AV fistula for renal replacement therapy, or abnormal Allen's test.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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120 participants in 2 patient groups

HPI group

Experimental group

Description:

Managing intraoperative hemodynamic condition under the HPI guidance

Treatment:

Device: BP management with HPI guidance

Standard care group

No Intervention group

Description:

Managing intraoperative hemodynamic condition with standard anesthesia care (blinding the HPI monitor screen)