Hypoxia in Flight Simulation in Obese Patients

Wissenschaftliches Institut Bethanien e.V

Status: Completed

Conditions: Obesity, COPD, OHS

Treatments: Other: flight simulationin obese healthy adults or obese patients with or without COPD, OHS

Study type: Observational

Funder types: Other

Identifiers

NCT02636465

WI_105/2013

Details and patient eligibility

About

The purpose of this pilot study is to determine whether obese adults,obese (BMI>30 kg/m2) with obesity hypoventilation or obese COPD-patients do undergo oxygen desaturation under flight simulation and if the hypoxic altitude simulation test is as effective as the hypoxic chamber test.

Enrollment: 21 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age ≥ 18 years
• patients with COPD (GOLD I-IV Group A-D) with obesity (BMI> 30kg/m2), obese healthy adults with BMI> 30kg /m2, patients with Obesity hypoventilation syndrome
• informed consent provided

Exclusion criteria

• patients less than BMI <30 kg/m2 with or without COPD, OHS
• Age < 18 years
• pregnancy, lactation
• any medical, psychological or other condition restricting the patient's ability to provide informed consent
• participation in another clinical trial

Trial design

21 participants in 3 patient groups

obese healthy adults

Description:

persons with BMI\> 30 kg/m2

Treatment:

Other: flight simulationin obese healthy adults or obese patients with or without COPD, OHS

obese COPD patients

Description:

COPD-patients (GOLD I-IV Group A-D) with BMI\> 30 kg/m2

Treatment:

Other: flight simulationin obese healthy adults or obese patients with or without COPD, OHS

OHS-patients

Description:

patients with defined OHS: BMI\>30 kg/m2 and sleep related breathing disease, no COPD

Treatment:

Other: flight simulationin obese healthy adults or obese patients with or without COPD, OHS