Iatrogenic Deficiencies in ICU Patients With Prolonged Continuous Renal Replacement Therapy (IBRIST)

Karolinska University Hospital

Status: Not yet enrolling

Conditions: Acute Kidney Injury

Treatments: Diagnostic Test: blood test

Study type: Observational

Funder types: Other

Identifiers

NCT06983197

2024-07642-01

Details and patient eligibility

About

ICU patients are recruited after at least 5 days treatment with continuous renal replacement therapy. Blood samples are drawn at time of recruitment and then every 3-5 days until ceseation of renal replacement therapy.

Samples will be analyzed for concentrations of trace elements, vitamins and amino acids.

10 adult ICU patients treated for two weeks without renal replacement therapy will be sampled at one time point to serve as controls.

Enrollment: 30 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria CRRT group:

• CRRT more than 5 days

Exclusion Criteria:

• N/A

Inclusion criteria non-CRRT group

• ICU care 10-15 days without any dialysis treatment

Trial design

30 participants in 2 patient groups

CRRT patients

Description:

Patients, all ages, that receive CRRT for at least five days.

Treatment:

Diagnostic Test: blood test

Non-CRRT patient

Description:

Adult patients, \>17 yo, treated in the ICU for 10-15 days without renal replacement therapy

Treatment:

Diagnostic Test: blood test