Iatrogenic Effects of Treatment for Childhood Cancer Constitution of a Biological Samples Bank (BIO-F)

Gustave Roussy

Status: Unknown

Conditions: Paediatric Malignancies

Treatments: Procedure: saliva samples; Procedure: blood samples

Study type: Observational

Funder types: Other

Identifiers

NCT02666625

2010-A00555-34

2010/1623 (Other Identifier)

Details and patient eligibility

About

The constitution of a biological samples bank, attached to epidemiological studies Cohort F-CCSS on iatrogenic effects of treatment of childhood cancer, will identify genetic variants that can modulate the iatrogenic risks of these treatments. The main objective is to provide a biological samples bank to consider, besides the carcinogenic risks, the risk of other iatrogenic diseases in these children, in particular cardiac, cerebrovascular, lung, bone and kidney. These conditions can be very incapacitating and in some cases, fatal. Their impact, however, is poorly estimated as occurring in adulthood, they are rarely made in relation to the treatment received in childhood. The overall project is expected to eventually better define the iatrogenic effects prevention strategies for cancer treatment.

Enrollment: 6,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients treated for a first cancer in childhood
• Adult patients
• Signed informed consent
• Patient insured or enjoying a social security scheme

Exclusion criteria

• Minor patients
• Under legal protection measure patients
• Refusal of consent

Trial design

6,000 participants in 1 patient group

Patients treated for cancer in childhood

Treatment:

Procedure: blood samples

Procedure: saliva samples