Ibuprofen Suppositories Administration in Infants and Children

Soroka University Medical Center

Status and phase: Unknown; Phase 4

Conditions: Fever

Treatments: Drug: ibuprofen suppositories

Study type: Interventional

Funder types: Other

Identifiers

NCT00938509

sor477208ctil

Details and patient eligibility

About

The study will evaluate the efficacy of Ibuprofen administered as suppositories in the treatment of fever in infants and children. Ibuprofen as suppositories is not yet registered in Israel, although widely used in Europe.

Full description

The drug will be used in 100 consecutive infants and children admitted with fever at the pediatric ER of the Soroka Medical Center. The information on the drug efficacy will be collected in appropriate parental questionnaires.

Enrollment: 100 estimated patients

Sex: All

Ages: 6 months to 12 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Infants and children with rectal temperature > 38.5 C

Exclusion criteria

• Infants < 6 months of age

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)